{"product_id":"memory-trio-cognitive-support-stack","title":"Memory Trio — Cognitive Support Stack  Sage, Rosemary \u0026 Bacopa","description":"\u003ch2\u003eMemory Trio — Cognitive Support Stack  Sage, Rosemary \u0026amp; Bacopa\u003c\/h2\u003e\n\u003cp\u003eYour brain runs on acetylcholine — the neurotransmitter behind memory, focus, arousal, and motivation. The Memory Trio works as a \u003cstrong\u003etriple-action acetylcholine preservation system\u003c\/strong\u003e: three botanicals, three compound classes, one unified mechanism. Individually potent. Together, unmatched.\u003c\/p\u003e\n\u003ch2\u003eHow It Works — The ACh Connection\u003c\/h2\u003e\n\u003cp\u003eAcetylcholine (ACh) is broken down in the brain by an enzyme called acetylcholinesterase (AChE). Low ACh is directly linked to memory loss, cognitive decline, Alzheimer's disease, and Parkinson's disease. All three herbs in this stack inhibit AChE — preserving ACh and keeping your brain sharp.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eOrganic Mediterranean Sage\u003c\/strong\u003e — terpenoids inhibit AChE, enhancing memory, attention, and cognitive function. Used since antiquity for mental clarity.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOrganic Rosemary\u003c\/strong\u003e — 1,8-cineole inhibits AChE and supports cerebral blood circulation. Carvacrol, a phenolic monoterpene in rosemary, crosses the blood-brain barrier and inhibits TRPM7 — a key amplifier of neuronal death in stroke and ischemia — reducing infarct volume by up to 44% in preclinical models.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBacopa Monnieri (Brahmi)\u003c\/strong\u003e — bacosides cross the blood-brain barrier and inhibit AChE, comparable in mechanism to Huperzine A. Bacopa also promotes synaptogenesis (new synapse formation), repairs neurons, reduces neuroinflammation, and modulates the cholinergic system. A cornerstone of Ayurvedic medicine for over 3,000 years.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eNaturally Occurring Compounds\u003c\/h2\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eHerb\u003c\/th\u003e\n\u003cth\u003eKey Compounds\u003c\/th\u003e\n\u003cth\u003ePrimary Actions\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSage\u003c\/td\u003e\n\u003ctd\u003eTerpenoids, rosmarinic acid\u003c\/td\u003e\n\u003ctd\u003eAChE inhibition, antioxidant, anti-inflammatory\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eRosemary\u003c\/td\u003e\n\u003ctd\u003e1,8-cineole, carvacrol, rosmarinic acid\u003c\/td\u003e\n\u003ctd\u003eAChE inhibition, TRPM7 inhibition, cerebral circulation\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBacopa\u003c\/td\u003e\n\u003ctd\u003eBacosides (12 analogs), brahmine, flavonoids\u003c\/td\u003e\n\u003ctd\u003eAChE inhibition, synaptogenesis, neuroprotection, anxiolytic\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch2\u003eTraditional Use\u003c\/h2\u003e\n\u003cp\u003eSage and Rosemary have been used in European herbal traditions since antiquity — both associated with memory, remembrance, and mental sharpness. Bacopa Monnieri has been a cornerstone of Ayurvedic medicine for over 3,000 years, traditionally prescribed to enhance learning, retention, and calm the nervous system under stress.\u003c\/p\u003e\n\u003ch2\u003eEmerging Research\u003c\/h2\u003e\n\u003cp\u003eBeyond cognitive support, emerging research suggests Bacopa Monnieri extract may have significant potential in oncology. In vitro studies indicate the ethanolic extract exhibits strong cytotoxicity against hepatocellular carcinoma (HCC) cells, with an IC50 of 24.70 μg\/mL and a reported 58.65% apoptosis rate against HepG2 cells — attributed to its rich bacoside, phenolic, and flavonoid content. Research is ongoing and these findings are preclinical.\u003c\/p\u003e\n\u003ch2\u003eHow to Use\u003c\/h2\u003e\n\u003cp\u003eTake each extract individually or combine in water or juice. Standard dose: 1–2ml per extract, 1–2x daily. Best taken consistently over 4–8 weeks for cumulative cognitive benefit. \u003cstrong\u003eBacopa is best taken with food\u003c\/strong\u003e to minimise digestive sensitivity.\u003c\/p\u003e\n\u003ch2\u003ePrecautions\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eNot recommended during pregnancy or breastfeeding without practitioner guidance.\u003c\/li\u003e\n\u003cli\u003eBacopa may interact with thyroid medications and cholinergic drugs — consult your healthcare provider if on prescription medication.\u003c\/li\u003e\n\u003cli\u003eBacopa may cause loose stools, gas, nausea, or digestive discomfort at higher doses — always take with food.\u003c\/li\u003e\n\u003cli\u003eIf you have a known medical condition or are undergoing cancer treatment, consult your healthcare provider before use.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eStack This With\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003ca href=\"\/products\/ginkgo-biloba-extract-ginkgo-biloba-memory-circulation-neuroprotection\"\u003eGinkgo Biloba Extract\u003c\/a\u003e\u003c\/strong\u003e — promotes higher acetylcholine concentrations in decision-making and short-term memory regions; supports cerebral blood circulation, enhancing delivery of ACh precursors to the brain. The ultimate complement to the Memory Trio.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003ca href=\"\/products\/8019335020606\"\u003eMagnesium Glycinate\u003c\/a\u003e\u003c\/strong\u003e — calms the nervous system, supports sleep quality and synaptic plasticity.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLion's Mane\u003c\/strong\u003e — stimulates Nerve Growth Factor (NGF) for neuroplasticity and neuroregeneration.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWant to Combine?\u003c\/h2\u003e\n\u003cp\u003eEach extract in the Memory Trio is available individually or as a customisable stack. Select your preferred size for each herb using the variant selectors above — mix and match 30ml, 50ml, or 100ml to suit your protocol.\u003c\/p\u003e\n\u003ch2\u003eRelated Wellness Guides\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/thegumpiiapothecary.com\/blogs\/news\/memory-trio-sage-rosemary-bacopa-cognitive-health\"\u003eThe Memory Trio: How Sage, Rosemary \u0026amp; Bacopa Support Cognitive Health\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eResearch \u0026amp; References\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.ijpsjournal.com\/article\/rosemary-salvia-rosmarinus-therapeutic-and-neurological-effects-of-rosemery-and-phytochemicals-and-biological-activity#\"\u003eRosemary (Salvia rosmarinus): Therapeutic and Neurological Effects — IJPS Journal\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC12036942\/\"\u003eSage: Cognitive and Neuroprotective Properties — PMC NIH\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0254629924002680\"\u003eBacopa monnieri: Anticancer Potential Against Hepatocellular Carcinoma — ScienceDirect\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.sciencedirect.com\/org\/science\/article\/abs\/pii\/S2210315525000198\"\u003eBacopa monnieri: Phytochemical \u0026amp; Cognitive Enhancement Profile — ScienceDirect\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003eKhojah \u0026amp; Al Dera: Neuroprotective Role of Carvacrol in Ischemic Brain Injury — Systematic Review (KAIMRC NRR25\/050\/9)\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"The Gumpii Apothecary","offers":[{"title":"30ml \/ 30ml \/ 30ml","offer_id":43099599142974,"sku":null,"price":120.0,"currency_code":"AUD","in_stock":true},{"title":"30ml \/ 30ml \/ 50ml","offer_id":43099599175742,"sku":null,"price":145.0,"currency_code":"AUD","in_stock":true},{"title":"30ml \/ 30ml \/ 100ml","offer_id":43099599208510,"sku":null,"price":190.0,"currency_code":"AUD","in_stock":true},{"title":"30ml \/ 50ml \/ 30ml","offer_id":43099599241278,"sku":null,"price":145.0,"currency_code":"AUD","in_stock":true},{"title":"30ml \/ 50ml \/ 50ml","offer_id":43099599274046,"sku":null,"price":170.0,"currency_code":"AUD","in_stock":true},{"title":"30ml \/ 50ml \/ 100ml","offer_id":43099599306814,"sku":null,"price":215.0,"currency_code":"AUD","in_stock":true},{"title":"30ml \/ 100ml \/ 30ml","offer_id":43099599339582,"sku":null,"price":190.0,"currency_code":"AUD","in_stock":true},{"title":"30ml \/ 100ml \/ 50ml","offer_id":43099599372350,"sku":null,"price":215.0,"currency_code":"AUD","in_stock":true},{"title":"30ml \/ 100ml \/ 100ml","offer_id":43099599405118,"sku":null,"price":260.0,"currency_code":"AUD","in_stock":true},{"title":"50ml \/ 30ml \/ 30ml","offer_id":43099599437886,"sku":null,"price":145.0,"currency_code":"AUD","in_stock":true},{"title":"50ml \/ 30ml \/ 50ml","offer_id":43099599470654,"sku":null,"price":170.0,"currency_code":"AUD","in_stock":true},{"title":"50ml \/ 30ml \/ 100ml","offer_id":43099599503422,"sku":null,"price":215.0,"currency_code":"AUD","in_stock":true},{"title":"50ml \/ 50ml \/ 30ml","offer_id":43099599536190,"sku":null,"price":170.0,"currency_code":"AUD","in_stock":true},{"title":"50ml \/ 50ml \/ 50ml","offer_id":43099599568958,"sku":null,"price":195.0,"currency_code":"AUD","in_stock":true},{"title":"50ml \/ 50ml \/ 100ml","offer_id":43099599601726,"sku":null,"price":240.0,"currency_code":"AUD","in_stock":true},{"title":"50ml \/ 100ml \/ 30ml","offer_id":43099599634494,"sku":null,"price":215.0,"currency_code":"AUD","in_stock":true},{"title":"50ml \/ 100ml \/ 50ml","offer_id":43099599667262,"sku":null,"price":240.0,"currency_code":"AUD","in_stock":true},{"title":"50ml \/ 100ml \/ 100ml","offer_id":43099599700030,"sku":null,"price":285.0,"currency_code":"AUD","in_stock":true},{"title":"100ml \/ 30ml \/ 30ml","offer_id":43099599732798,"sku":null,"price":190.0,"currency_code":"AUD","in_stock":true},{"title":"100ml \/ 30ml \/ 50ml","offer_id":43099599765566,"sku":null,"price":215.0,"currency_code":"AUD","in_stock":true},{"title":"100ml \/ 30ml \/ 100ml","offer_id":43099599798334,"sku":null,"price":260.0,"currency_code":"AUD","in_stock":true},{"title":"100ml \/ 50ml \/ 30ml","offer_id":43099599831102,"sku":null,"price":215.0,"currency_code":"AUD","in_stock":true},{"title":"100ml \/ 50ml \/ 50ml","offer_id":43099599863870,"sku":null,"price":240.0,"currency_code":"AUD","in_stock":true},{"title":"100ml \/ 50ml \/ 100ml","offer_id":43099599896638,"sku":null,"price":285.0,"currency_code":"AUD","in_stock":true},{"title":"100ml \/ 100ml \/ 30ml","offer_id":43099599929406,"sku":null,"price":260.0,"currency_code":"AUD","in_stock":true},{"title":"100ml \/ 100ml \/ 50ml","offer_id":43099599962174,"sku":null,"price":285.0,"currency_code":"AUD","in_stock":true},{"title":"100ml \/ 100ml \/ 100ml","offer_id":43099599994942,"sku":null,"price":330.0,"currency_code":"AUD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0611\/9997\/4462\/files\/BRAINTRIO.png?v=1784428281","url":"https:\/\/thegumpiiapothecary.com\/products\/memory-trio-cognitive-support-stack","provider":"The Gumpii Apothecary","version":"1.0","type":"link"}