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The Gumpii Apothecary

Memory Trio — Cognitive Support Stack Sage, Rosemary & Bacopa

Memory Trio — Cognitive Support Stack Sage, Rosemary & Bacopa

$120.00 AUD
$120.00 AUD
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Bacopa Monnieri Extract (Product Size)
Organic Mediterranean Sage Extract (Product Size)
Organic Rosemary Extract (Product Size)

Memory Trio — Cognitive Support Stack  Sage, Rosemary & Bacopa

Your brain runs on acetylcholine — the neurotransmitter behind memory, focus, arousal, and motivation. The Memory Trio works as a triple-action acetylcholine preservation system: three botanicals, three compound classes, one unified mechanism. Individually potent. Together, unmatched.

How It Works — The ACh Connection

Acetylcholine (ACh) is broken down in the brain by an enzyme called acetylcholinesterase (AChE). Low ACh is directly linked to memory loss, cognitive decline, Alzheimer's disease, and Parkinson's disease. All three herbs in this stack inhibit AChE — preserving ACh and keeping your brain sharp.

  • Organic Mediterranean Sage — terpenoids inhibit AChE, enhancing memory, attention, and cognitive function. Used since antiquity for mental clarity.
  • Organic Rosemary — 1,8-cineole inhibits AChE and supports cerebral blood circulation. Carvacrol, a phenolic monoterpene in rosemary, crosses the blood-brain barrier and inhibits TRPM7 — a key amplifier of neuronal death in stroke and ischemia — reducing infarct volume by up to 44% in preclinical models.
  • Bacopa Monnieri (Brahmi) — bacosides cross the blood-brain barrier and inhibit AChE, comparable in mechanism to Huperzine A. Bacopa also promotes synaptogenesis (new synapse formation), repairs neurons, reduces neuroinflammation, and modulates the cholinergic system. A cornerstone of Ayurvedic medicine for over 3,000 years.

Naturally Occurring Compounds

Herb Key Compounds Primary Actions
Sage Terpenoids, rosmarinic acid AChE inhibition, antioxidant, anti-inflammatory
Rosemary 1,8-cineole, carvacrol, rosmarinic acid AChE inhibition, TRPM7 inhibition, cerebral circulation
Bacopa Bacosides (12 analogs), brahmine, flavonoids AChE inhibition, synaptogenesis, neuroprotection, anxiolytic

Traditional Use

Sage and Rosemary have been used in European herbal traditions since antiquity — both associated with memory, remembrance, and mental sharpness. Bacopa Monnieri has been a cornerstone of Ayurvedic medicine for over 3,000 years, traditionally prescribed to enhance learning, retention, and calm the nervous system under stress.

Emerging Research

Beyond cognitive support, emerging research suggests Bacopa Monnieri extract may have significant potential in oncology. In vitro studies indicate the ethanolic extract exhibits strong cytotoxicity against hepatocellular carcinoma (HCC) cells, with an IC50 of 24.70 μg/mL and a reported 58.65% apoptosis rate against HepG2 cells — attributed to its rich bacoside, phenolic, and flavonoid content. Research is ongoing and these findings are preclinical.

How to Use

Take each extract individually or combine in water or juice. Standard dose: 1–2ml per extract, 1–2x daily. Best taken consistently over 4–8 weeks for cumulative cognitive benefit. Bacopa is best taken with food to minimise digestive sensitivity.

Precautions

  • Not recommended during pregnancy or breastfeeding without practitioner guidance.
  • Bacopa may interact with thyroid medications and cholinergic drugs — consult your healthcare provider if on prescription medication.
  • Bacopa may cause loose stools, gas, nausea, or digestive discomfort at higher doses — always take with food.
  • If you have a known medical condition or are undergoing cancer treatment, consult your healthcare provider before use.

Stack This With

  • Ginkgo Biloba Extract — promotes higher acetylcholine concentrations in decision-making and short-term memory regions; supports cerebral blood circulation, enhancing delivery of ACh precursors to the brain. The ultimate complement to the Memory Trio.
  • Magnesium Glycinate — calms the nervous system, supports sleep quality and synaptic plasticity.
  • Lion's Mane — stimulates Nerve Growth Factor (NGF) for neuroplasticity and neuroregeneration.

Want to Combine?

Each extract in the Memory Trio is available individually or as a customisable stack. Select your preferred size for each herb using the variant selectors above — mix and match 30ml, 50ml, or 100ml to suit your protocol.

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Research & References

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