Nattokinase

Nattokinase

Nattokinase is a naturally occurring enzyme derived from natto — a traditional Japanese food made from fermented soybeans that has been consumed for over a thousand years. The enzyme was first identified and isolated by Japanese researcher Dr. Hiroyuki Sumi in 1980, and has since been the subject of extensive scientific research.

This product provides 2000 Fibrinolytic Units (FU) per 100mg capsule — the standard unit of measurement for nattokinase potency. Sourced from non-GMO soy.

About Nattokinase

Nattokinase is a serine protease enzyme — a class of enzymes that act on proteins. It is naturally produced during the fermentation of soybeans by the bacterium Bacillus subtilis natto. It is one of the most extensively researched food-derived enzymes in cardiovascular and circulatory wellness research.

Natto itself has been a staple of traditional Japanese cuisine for centuries, particularly in the Kanto region, and is associated with the longevity traditions of Japanese dietary culture.

Potency

• 2000 FU (Fibrinolytic Units) per capsule — 100mg
• FU is the internationally recognised unit for measuring nattokinase enzymatic activity
• Non-GMO soy source

Areas of Scientific Research Interest

Cardiovascular & Circulatory Wellness Research

Nattokinase has attracted significant research interest for its potential role in cardiovascular wellness. It works by breaking down fibrin — a protein involved in blood clotting — and research has explored its potential associations with blood flow and healthy circulation. This makes it one of the most studied food-derived enzymes in cardiovascular wellness research.

Blood Pressure Research

Some studies have explored nattokinase's potential associations with healthy blood pressure levels, including research into vasodilation and endothelial function. These are emerging areas of ongoing scientific investigation.

Circulation Research

By supporting the body's natural fibrinolytic processes, nattokinase has been studied in the context of circulation and blood flow wellness. This has made it a subject of ongoing interest in cardiovascular wellness research.

Inflammatory Research Interest

Nattokinase has been explored in research for potential associations with inflammatory markers. The relationship between fibrinolytic activity and inflammation is an active area of scientific investigation.

Research Interest

Nattokinase has been the subject of growing peer-reviewed scientific investigation and has been discussed by researchers and clinicians in the context of cardiovascular and longevity research. Expert references cited here are for educational context only and do not constitute endorsement of this product.

How to Use

Take 1–2 capsules between meals, or as directed by your healthcare practitioner. Best taken away from food for optimal enzymatic activity.

Important Precautions

Do not take if you are:

• Pregnant or breastfeeding
• Taking blood-thinning medications (including warfarin, aspirin, clopidogrel, or other anticoagulants) — nattokinase has fibrinolytic activity and may interact with these medications
• Allergic to soy or soy-derived products
• Scheduled for surgery — discontinue at least 2 weeks prior

Consult your healthcare practitioner before use if you have any cardiovascular condition, bleeding disorder, or are taking any medications.

Stack This With

• Gumpii Extract — foundational botanical base
• Cayenne Extract — traditional circulatory herb
• Magnesium Glycinate — nervous system and cardiovascular wellness support

Related Wellness Guides

• Wellness Hub — explore all herbal guides

Content provided for informational purposes only. Not medical advice. Not intended to diagnose, treat, or cure any condition. Consult your healthcare practitioner.