Australian Gumpii Extract - BEST SELLER

Australian Gumpii Extract (Pittosporum angustifolium)

Gumpii is a native Australian tree with deep roots in traditional Aboriginal bush medicine. Harvested from carefully selected trees and extracted in 60% alcohol, this small-batch extract delivers a broad spectrum of naturally occurring plant compounds in a concentrated liquid form.

This is our flagship product and the foundation of The Gumpii Apothecary range. Gumpii is also known as Gumby, Cumbi, desert apricot to name a few.

Traditional Use

Gumpii has been used for generations in Aboriginal bush medicine as a broad-support botanical — applied across multiple body systems to restore balance and resilience. All parts of the plant — leaf, bark, root, flower, fruit pulp, seed and wood — have documented traditional applications. It has been used historically for inflammatory, spasmodic, malarial and microbial conditions including chronic bronchitis, rheumatic complaints, sciatica, chest infections, skin diseases, and general immune support (Madikizela & McGaw, summarised in Phan et al., 2020).

Gumpii & Green Tea — Australia’s Answer to One of the World’s Most Studied Botanicals

Green tea is one of the most researched plants on earth — celebrated globally for its polyphenol richness, antioxidant capacity, and broad biological activity. Gumpii shares striking similarities at a phytochemical level, while offering a broader and more complex compound profile that green tea simply doesn’t have.

Compound / Property	Green Tea	Gumpii (Pittosporum angustifolium)
Phenolic acids (chlorogenic, caffeic, ferulic)	✅ Present	✅ Present — identified in HPLC profiling
Flavonoids (antioxidant, anti-inflammatory)	✅ Rich source (EGCG, catechins)	✅ Rich source — “nature’s biological response modifiers”
Tannins (astringent, antimicrobial)	✅ Present	✅ Present — vascular tonic, tissue protective
Antioxidant activity	✅ High	✅ High — free radical scavenging confirmed
Antimicrobial activity	✅ Moderate	✅✅ Broad-spectrum — 11+ clinically significant bacteria and fungi
Cancer cell line research	✅ Extensive (EGCG)	✅ Confirmed — most cytotoxic of all Australian native plants tested against HeLa and HT29 cells
Saponins (immune modulating, hepatoprotective)	❌ Absent	✅✅ Major compound class — unique to Gumpii
Alkaloids (broad biological activity)	❌ Absent	✅ Present — pharmacologically active
Phytoestrogens / triterpenoid saponins	❌ Absent	✅ Present — hormonal modulation, bone health
DNA topoisomerase I inhibition	❌ Not documented	✅ Confirmed — acylated triterpene saponins (Bäcker et al., 2016)

Think of Gumpii as Australia’s answer to green tea — with a broader, more complex phytochemical profile. Where green tea’s power lies primarily in its catechin flavonoids (especially EGCG), Gumpii adds saponins, alkaloids, phytoestrogens, and triterpenoid compounds that green tea simply doesn’t contain — giving it a wider reach across body systems.

This comparison is for educational purposes. Not medical advice.

Dosage Guide

Tincture: 6–12 drops in water per day. Dose is dependent on the individual and the condition being supported. Can be used daily as part of a broader wellness routine.

Side Effects: To date there have been no recorded side effects or contraindications with other medications. Always consult your healthcare practitioner.

Stack This With

• Firewater Alcohol Extract — concentrated broad-spectrum support
• X-CV Firewater — daily tonic use
• Magnesium Glycinate — recovery and nervous system support
• Glycine — rest and deep recovery

Want to Combine Several Tinctures?

We'll blend them into one bottle for you — saving you money and simplifying your routine. Find out more →

Related Wellness Guides

• Gumpii — Traditional Botanical Overview
• Immune, Respiratory & Infections Support
• Gumpii & Antimicrobial Resistance — Research Overview
• Wellness Hub — explore all herbal guides

Phytochemistry — What’s Inside

Gumpii contains a remarkable and complex profile of naturally occurring bioactive compounds:

Saponins

• Hepatoprotective — Kupffer cell support in the liver promoting detoxification
• Adaptogenic — adrenal tonic, hormone modulating
• Expectorant — stimulates mucociliary escalator
• Diuretic — via local stimulation of kidney epithelia
• Cholesterol lowering — binds with cholesterol preventing reabsorption
• Cellular Health — antioxidant effect, direct cytotoxicity of malignant cells, immune modulation
• Gentle systemic detoxifier
• Accelerates absorption of other active compounds

Research has identified acylated triterpene saponins in Pittosporum angustifolium with the ability to inhibit DNA topoisomerase I activity (Bäcker et al., 2016).

Tannins

• Tighten tissues — useful for varicose veins and vascular integrity
• Reduce excessive secretions
• Protect damaged tissue — skin repair and wound support
• Antimicrobial and anti-inflammatory
• Keratolytic properties supporting skin conditions

Flavonoids

• Potent antioxidants — resonance stabilisation of damaging free radicals
• Smooth muscle relaxation — antispasmodic and hypotensive effects
• Reduced platelet aggregation and blood vessel protection
• Enhanced neural transmission and neuroprotective effects
• Reduced capillary fragility via collagen crosslinking
• Increased intracellular Vitamin C availability
• Reduced allergic responses and inflammatory leukotrienes
• Prevention of LDL oxidation
• Liver-protective and phytoestrogenic activity

Phytoestrogens & Triterpenoid Saponins

• Cellular health — reducing effects of endogenous estrogens
• Bone health — inhibit bone resorption and promote remineralisation
• PCOS support — anti-inflammatory and modulation of the hypothalamic-pituitary-ovarian axis
• Menopause — may reduce hot flashes without increasing estradiol

Alkaloids & Coumarins

Pharmacologically active nitrogen-bearing compounds contributing broad biological activity. Coumarins add anti-inflammatory, antispasmodic, anti-oedematous, and vascular tonic effects.

University Research — Validating Traditional Use

A 2007 study at Ernst-Moritz-Arndt University Greifswald, Germany examined Pittosporum phillyraeoides extracts at a cellular level:

• Extracts demonstrated weak to moderate cytotoxicity against FL cells and lung cell line A427
• The Amylase-treated extract — mimicking the traditional Aboriginal preparation — showed notable cytotoxic and immune-stimulating effects against malignant cells
• Concentrations cytotoxic to malignant cells showed a stimulating effect on healthy human blood leucocytes
• Extracts stimulated production of Tumour Necrosis Factor α, indicating immunomodulatory properties

“At least in vitro a suppression of malignant cell growth was shown.” — S.H., Greifswald, July 2007

A further study in Natural Products and Bioprospecting (SAGE Journals) assessed cytotoxic activity against HeLa and HT29 colorectal cancer cell lines:

• Pittosporum angustifolium was the most cytotoxic species tested against both HeLa and HT29 cells
• HPLC profiling revealed a diverse range of therapeutic phenolic compounds

“The Australian species Pittosporum angustifolium was the most cytotoxic against HeLa and HT29 cells comparing to the other plant extracts tested.” — Mani et al., SAGE Journals

Laboratory Research Context — Understanding the Cell Lines

• HeLa cells — a human cervical cancer cell line, one of the most widely used in biological and medical research worldwide. Named after Henrietta Lacks, HeLa cells have been used in cancer research for over 70 years.
• HT29 cells — a human colorectal adenocarcinoma cell line, commonly used in laboratory studies investigating compounds with potential activity against colon cancer cells.

These are standard laboratory research models. Results in cell line studies do not predict outcomes in humans and do not constitute clinical evidence of efficacy. Not medical advice. Not intended to diagnose, treat, or cure any condition.

Antimicrobial Activity — Research Data

Laboratory studies confirm inhibitory activity against a broad range of clinically significant bacteria and fungi, including:

Bacteria: Klebsiella pneumoniae, Proteus mirabilis, Proteus vulgaris, Serratia marcescens, Pseudomonas aeruginosa, Acinetobacter baylyi, Staphylococcus aureus, Streptococcus pyogenes, Escherichia coli, Bacillus subtilis, Salmonella typhimurium

Fungi: Candida albicans, Aspergillus niger

Key Areas of Traditional & Researched Application

• Immune Support — broad-spectrum immune modulation
• Antioxidant — powerful free radical scavenging
• Anti-inflammatory — joint, skin, and systemic inflammatory conditions
• Circulation & Blood Pressure — peripheral circulation and cardiovascular support
• Cholesterol & Triglycerides — saponin binding mechanism
• Detoxification — blood cleansing and lymphatic function
• Skin Health — eczema, psoriasis, pruritus, acne, rashes
• Digestive Health — gut function, spastic colon, cramping
• Anti-viral — colds, flu, viral support
• Chronic Fatigue — persistent fatigue and low energy
• Bone Health — inhibits bone resorption, supports remineralisation
• Hormonal Balance — PCOS, menopause, estrogen modulation
• Meniere’s Disease — vertigo, tinnitus, and balance issues
• Mood & Emotional Wellbeing — sadness, melancholy, despondency
• Respiratory Health — chronic lung conditions and breathing difficulties

Our Extraction Method

The Gumpii Apothecary uses the Swiss method of ethanol extraction. We typically use a 60% ethanol base for robust botanicals, and 45% ethanol for more fragile flora. Product labels and images are a guide only — alcohol concentration may vary by botanical and batch.

Featured Research

Published laboratory research confirms that Pittosporum angustifolium extracts strongly inhibit the growth of Klebsiella pneumoniae and Proteus mirabilis — bacterial triggers of autoimmune inflammatory disease — and have demonstrated activity against Ross River virus-induced cytopathicity.

→ Read the full research overview

Research References

1. Phan, A. D. T. et al. (2020). Foods, 9(7), 887. doi.org
2. Vesoul, J. & Cock, I. (2011). Pharmacognosy Communications. Griffith University
3. Beh, C. & Teoh, W. H. (2022). Nutraceuticals, 2(2), 49–59. doi.org
4. Mani, J. et al. (2022). In vitro cytotoxicity against HeLa and HT29 cell lines. Natural Products and Bioprospecting. SAGE Journals
5. Bäcker, C. et al. (2016). DNA-topoisomerase I inhibition by acylated triterpene saponins. Natural Products and Bioprospecting, 6(2). PubMed
6. S.H. (2007). Biological and chemical examination of Pittosporum phillyraeoides. Ernst-Moritz-Arndt University Greifswald.
7. Saifi, S. et al. (2024). Fitoterapia, 173, 105811. doi.org

What Our Customers Say

⭐⭐⭐⭐⭐ “I had a Staphylococcus bug and sprayed your GG tincture under my tongue. The swelling went in 24 hours and the pain is almost gone. To me it’s a miracle.” — Irene

⭐⭐⭐⭐⭐ “I’m 62, work and very active. I decided to give the Gumpii Gumpii a trial run to boost my immune system — and boost it, it did. I have more energy, my workouts are easier and I’m able to train longer without tiring.” — Gunther

⭐⭐⭐⭐⭐ “I originally suffered from pain and locking of the fingers up to 20 times a day. After taking the arthritis tincture — immediate help with pain and stiffness within 2 weeks, locking resolved in 2–3 weeks, and 3 months later I have normal use of both hands.” — Steve Shaw

⭐⭐⭐⭐⭐ “My biggest win from discovering Gumpii Gumpii has been the relief from painful outbreaks I used to suffer regularly. Relief is obtained within hours of taking the Gumpii Gumpii tincture.” — D. Barry, Gold Coast

Content provided for informational purposes only. Not medical advice. Not intended to diagnose, treat, or cure any condition. Consult your healthcare practitioner.