Australian Gumpii Extract - BEST SELLER

Australian Gumpii Extract (Pittosporum angustifolium)

Gumpii is a native Australian tree with deep roots in traditional Aboriginal bush medicine. Harvested from carefully selected trees and extracted in 60% alcohol, this small-batch extract delivers a broad spectrum of naturally occurring plant compounds in a concentrated liquid form.

This is our flagship product and the foundation of The Gumpii Apothecary range. Gumpii is also known as Gumby, Cumbi, desert apricot to name a few.

Traditional Use

Gumpii has been used for generations in Aboriginal bush medicine as a broad-support botanical — applied across multiple body systems to restore balance and resilience. All parts of the plant — leaf, bark, root, flower, fruit pulp, seed and wood — have documented traditional applications. It has been used historically for inflammatory, spasmodic, malarial and microbial conditions including chronic bronchitis, rheumatic complaints, sciatica, chest infections, skin diseases, and general immune support (Madikizela & McGaw, summarised in Phan et al., 2020).

Dosage Guide

Tincture: 6–12 drops in water per day. Dose is dependent on the individual and the condition being supported. Can be used daily as part of a broader wellness routine.

Side Effects: To date there have been no recorded side effects or contraindications with other medications. Always consult your healthcare practitioner.

Stack This With

• Firewater Alcohol Extract — concentrated broad-spectrum support
• X-CV Firewater — daily tonic use
• Magnesium Glycinate — recovery and nervous system support
• Glycine — rest and deep recovery

Want to Combine Several Tinctures?

We'll blend them into one bottle for you — saving you money and simplifying your routine. Find out more →

Related Wellness Guides

• Gumpii — Traditional Botanical Overview
• Immune, Respiratory & Infections Support
• Gumpii & Antimicrobial Resistance — Research Overview
• Wellness Hub — explore all herbal guides

Phytochemistry — What's Inside

Gumpii contains a remarkable and complex profile of naturally occurring bioactive compounds. Each compound class contributes distinct and overlapping properties:

Saponins

Saponins are a major part of the plant's active immune system — functioning as a "natural antibiotic" for the plant and a powerful systemic support agent in the body. Key actions include:

• Hepatoprotective — Kupffer cell support in the liver promoting detoxification
• Adaptogenic — adrenal tonic effect, hormone modulating by mimicking endogenous hormones and sparing cortisol
• Expectorant — stimulates mucociliary escalator and mucous membrane activity
• Diuretic — via local stimulation of kidney epithelia
• Cholesterol lowering — binds with cholesterol preventing reabsorption and increasing excretion
• Cellular Health — proposed mechanisms include antioxidant effect, direct cytotoxicity of malignant cells, immune modulation, and interference with malignant cell membrane cholesterol
• Gentle systemic detoxifier — eliminates toxic buildup throughout the body
• Accelerates absorption of other active compounds

Research has identified acylated triterpene saponins in Pittosporum angustifolium with the ability to inhibit DNA topoisomerase I activity — indicating significant biochemical activity at a cellular level (Bäcker et al., 2016).

Note: Saponins are comparatively harmless when taken orally. Cholesterin inactivates them so that only mucus membranes are affected.

Tannins

Polyphenolic compounds that contract and astringe tissues. Key actions include:

• Tighten tissues — useful for varicose veins and vascular integrity
• Reduce excessive secretions — diarrhoea, heavy menstrual flow
• Protect damaged tissue — skin repair and wound support
• Antimicrobial and anti-inflammatory via inhibition of 5-lipoxygenase and hyaluronidase
• Keratolytic properties supporting skin conditions

Flavonoids

Referred to as "nature's biological response modifiers" or Redox Regulators. Major actions include:

• Potent antioxidants — resonance stabilisation of damaging free radicals
• Smooth muscle relaxation — antispasmodic and hypotensive effects
• Reduced platelet aggregation and blood vessel protection
• Enhanced neural transmission and neuroprotective effects
• Reduced capillary fragility via collagen crosslinking
• Increased intracellular Vitamin C availability
• Reduced allergic responses and inflammatory leukotrienes
• Prevention of LDL oxidation
• Liver-protective and phytoestrogenic activity

Phytoestrogens & Triterpenoid Saponins

Plant molecules with structural similarity to endogenous estrogens — but up to 400 times weaker in activity, making them modulatory rather than stimulatory. Key applications include:

• Cellular health — reducing effects of endogenous estrogens, particularly in pre-menopausal and obese post-menopausal women
• Bone health — inhibit bone resorption and promote remineralisation (relevant to osteoporosis)
• PCOS support — potent anti-inflammatory and modulation of the hypothalamic-pituitary-ovarian axis
• Menopause — may reduce hot flashes without increasing estradiol

Alkaloids & Coumarins

Pharmacologically active nitrogen-bearing compounds contributing broad biological activity. Coumarins add anti-inflammatory, antispasmodic, anti-oedematous, and vascular tonic effects.

University Research — Validating Traditional Use

A 2007 study conducted at the Institute of Pharmacy, Ernst-Moritz-Arndt University Greifswald, Germany examined Pittosporum phillyraeoides (Gumby Gumby) extracts at a cellular level. Key findings:

• Extracts demonstrated weak to moderate cytotoxicity against FL cells and lung cell line A427 — with polar ethanolic and water extracts showing the highest activity
• The Amylase-treated extract — which mimics the traditional Aboriginal preparation method of breaking down the leaves — showed notable cytotoxic and immune-stimulating effects against malignant cells
• Concentrations cytotoxic to malignant cells showed a stimulating effect on healthy human blood leucocytes — a critical distinction
• Extracts stimulated human blood cells to produce Tumour Necrosis Factor α up to cytotoxic concentrations, indicating immunomodulatory properties

"The effects observed in the in vitro studies correspond to the clinical observations of the assumed therapeutical benefit of Gumby Gumby in patients with malignant cell activity. At least in vitro a suppression of malignant cell growth was shown." — S.H., Greifswald, July 2007

Antimicrobial Activity — Research Data

Laboratory studies confirm inhibitory activity against a broad range of clinically significant bacteria and fungi (Vesoul & Cock, 2011; Phan et al., 2020; Beh & Teoh, 2022), including:

Bacteria: Klebsiella pneumoniae, Proteus mirabilis, Proteus vulgaris, Serratia marcescens, Pseudomonas aeruginosa, Acinetobacter baylyi, Staphylococcus aureus, Streptococcus pyogenes, Escherichia coli, Bacillus subtilis, Salmonella typhimurium

Fungi: Candida albicans, Aspergillus niger

Methanol and water were identified as the most efficient extraction solvents, yielding the broadest diversity of phytochemical classes and the strongest antimicrobial activity.

Key Areas of Traditional & Researched Application

• Immune Support — broad-spectrum immune modulation
• Antioxidant — powerful free radical scavenging supporting cardiovascular and cellular health
• Anti-inflammatory — supports joint, skin, and systemic inflammatory conditions including arthritis and autoimmune presentations
• Circulation & Blood Pressure — assists regulation of blood pressure and improves peripheral circulation; supports prevention of cardiovascular events, angina, and vascular problems
• Cholesterol & Triglycerides — supports healthy levels via saponin binding mechanism
• Detoxification — high saponin content supports blood cleansing and lymphatic function
• Skin Health — eczema, psoriasis, pruritus, acne, rashes, and skin repair
• Digestive Health — supports healthy gut function, spastic colon, mucous colitis, nervous colon, inflammation of the diverticula, cramping, and gastrointestinal comfort
• Anti-viral — traditionally used to support the body against viral invaders including colds and flu
• Chronic Fatigue — used with reported success in supporting persistent fatigue and low energy
• Bone Health — inhibits bone resorption and supports remineralisation
• Hormonal Balance — PCOS, menopause, and estrogen modulation
• Meniere's Disease — one of the few traditional botanicals noted for vertigo, tinnitus, and balance issues
• Mood & Emotional Wellbeing — traditionally used to support feelings of sadness, melancholy, and despondency by increasing blood flow and building immunity
• Respiratory Health — traditionally used to support chronic lung conditions characterised by damage to the air sacs, leading to breathing difficulties

Our Extraction Method

The Gumpii Apothecary uses the Swiss method of ethanol extraction for all alcohol-based botanical extracts. We typically use a 60% ethanol base for robust botanicals, and 45% ethanol for more fragile flora. Product labels and images are a guide only — alcohol concentration may vary by botanical and batch.

Featured Research

Published laboratory research confirms that Pittosporum angustifolium extracts strongly inhibit the growth of Klebsiella pneumoniae and Proteus mirabilis — bacterial triggers of autoimmune inflammatory disease — and have demonstrated activity against Ross River virus-induced cytopathicity in laboratory studies. Some combinations with conventional antibiotics also showed synergistic effects.

→ Read the full research overview

Research References

1. Phan, A. D. T. et al. (2020). Nutritional value and antimicrobial activity of Pittosporum angustifolium (Gumby Gumby). Foods, 9(7), 887. https://doi.org/10.3390/foods9070887
2. Vesoul, J. & Cock, I. (2011). Medicinal potential of Pittosporum phylliraeoides: antibacterial and antifungal activities. Pharmacognosy Communications. Griffith University Repository
3. Beh, C. & Teoh, W. H. (2022). Recent advances in the extraction of Pittosporum angustifolium. Nutraceuticals, 2(2), 49–59. https://doi.org/10.3390/nutraceuticals2020004
4. Mani, J. et al. (2022). In vitro cytotoxicity of crude polar extracts of Australian plants including P. angustifolium. Clinical Complementary Medicine and Pharmacology. ResearchGate
5. Bäcker, C. et al. (2016). Inhibition of DNA-topoisomerase I by acylated triterpene saponins from Pittosporum angustifolium. Natural Products and Bioprospecting, 6(2), 141–147. PubMed
6. S.H. (2007). Biological and chemical examination of Pittosporum phillyraeoides. Institute of Pharmacy, Ernst-Moritz-Arndt University Greifswald, Germany.
7. Saifi, S. et al. (2024). Insights into the preventive actions of natural compounds against Klebsiella pneumoniae infections and drug resistance. Fitoterapia, 173, 105811. https://doi.org/10.1016/j.fitote.2023.105811

What Our Customers Say

⭐⭐⭐⭐⭐ "I had a Staphylococcus bug and sprayed your GG tincture under my tongue. The swelling went in 24 hours and the pain is almost gone. To me it's a miracle." — Irene

⭐⭐⭐⭐⭐ "I'm 62, work and very active. I decided to give the Gumpii Gumpii a trial run to boost my immune system — and boost it, it did. I have more energy, my workouts are easier and I'm able to train longer without tiring. I will be using this product as a daily immune booster." — Gunther

⭐⭐⭐⭐⭐ "My son tried your tincture with some GG on plantar warts — it works a treat and no pain the next day or since!" — Elijah

⭐⭐⭐⭐⭐ "I originally suffered from pain and locking of the fingers up to 20 times a day when tying shoe laces, opening bottles and lifting. While a massage gun helped with pain relief, it was only when I took the arthritis tincture that I saw real improvements — immediate help with pain and stiffness within 2 weeks, locking resolved in 2-3 weeks, and 3 months later I have normal use of both hands with minimal twinges when lifting heavy objects." — Steve Shaw

⭐⭐⭐⭐⭐ "I was bitten by a white tail spider — my leg blew up and looked as if it was going to burst. I dribbled Wilga tincture over it and it immediately lost some of the inflammation. An hour later I rubbed it with the Wilga & Gumpii Cream, then started poulticing twice a day. The local health shop confirmed it was a white tail bite and said my leg was better than a doctor would have had it." — Jen

⭐⭐⭐⭐⭐ "My biggest win from discovering Gumpii Gumpii has been the relief from painful outbreaks I used to suffer regularly. Relief is obtained within hours of taking the Gumpii Gumpii tincture. I thoroughly recommend it." — D. Barry, Gold Coast

Content provided for informational purposes only. Not medical advice. Not intended to diagnose, treat, or cure any condition. Consult your healthcare practitioner.